
Could Semaglutide, Tirzepatide and Retatrutide Quiet Alcohol and Drug Cravings?
Three semaglutide trials report less heavy drinking or craving, while tirzepatide reduced alcohol reward in rodents. Here is what researchers know.
Reporting and analysis from the Research Pep News inaugural archive.

Three semaglutide trials report less heavy drinking or craving, while tirzepatide reduced alcohol reward in rodents. Here is what researchers know.

GLP-1 withdrawal trials show common weight regain. New 2026 evidence tests continued and reduced-dose maintenance—and exposes the questions left open.

A flat scale or returning appetite can make dose escalation feel obvious. The evidence says to check the trend, waist, strength, adherence and side effects first.

GH-releasing peptides amplify feedback-regulated signaling instead of activating androgen receptors. Here is why they may carry less risk than steroids.

Tesamorelin has FDA approval and visceral-fat trial data. CJC-1295 DAC and the no-DAC form stimulate growth-hormone signaling through different research paths.

Rat studies link BPC-157 to nitric-oxide signaling and altered vascular tone. Human blood-pressure and drug-interaction evidence remains nearly absent.

GLP-1 and retatrutide trials show that most weight lost is fat, while lean tissue also falls. What protein, strength training and older adults need to know.

Not losing weight after four weeks on semaglutide or tirzepatide? Dose-escalation schedules and SURMOUNT-1 data explain why some GLP-1 responses arrive later.

Researchers report early findings involving a naturally occurring peptide and a potential path for further melanoma research.

Oral absorption, enzymatic degradation, stability, and transport continue to make peptide delivery a demanding scientific problem.

Generative design, structure prediction, and computational screening are changing how researchers identify early peptide candidates.

Peptide studies in hypertension, osteochondral regeneration and bioactive extraction show how widely the field is expanding across modern research.

A detailed review of peptide discovery, production, delivery and approved applications explains where therapeutic peptide research may move next.

The Journal of Peptide Science serves the European Peptide Society and publishes research spanning peptide chemistry, biology, synthesis and applications.

Computational design, synthesis, analytical testing, manufacturing and regulation are changing together across the new era of peptide research.

Ring-shaped molecular architecture is opening new questions in target binding, synthesis, screening, analytics, and manufacturing.